Published 
– Join our new biotech developing curative cell therapy to late stage cancer – Are you dreaming of shaping a new biotech company and developing curative treatment to cancer? Are you highly experienced in developing cell based analytical assays from biotech or large pharma and want to use your capacity to catalyze a new cell therapy to cancer? – then read on.

About PokeAcell

PokeAcell is a newly establish biotech company with a proprietary technology for personalized T-cell therapy preparing for phase I in melanoma. We are an experienced team of science and business leaders founding PokeAcell with the vision to provide curative treatment to late stage cancer patients, where no treatment is available today. Our T cell therapy hold the promise of curative treatment in Melanoma and Merkel Cell carcinoma – two of the most severe skin cancers today and with potential in several other indications.

The position

We are seeking a lab based creative, self-motivated, detail-oriented and highly experienced scientist with a proven background in development and validation of new immune- and cell-based assays.

Your core responsibilities will be to:

  • Develop and execute new cell based functional (potency) assays
  • Develop and execute new characterization, release and stability assays
  • Establish analytical development/QC labs within PokeAcell
  • Validate and transfer functional assay to a QC environment, internal or with external partners
  • Execute experimental plans, analyse experimental data, maintain experimental results in relevant databases
  • Prepare, review and complete study reports and protocols/SOPs

In addition, you will shape PokeAcell together with us to establish a professional and cutting-edge cell therapy company. The job is located in Copenhagen with some activities taking place at DTU in Lyngby.

Qualifications

You hold a PhD or MS degree in Biochemistry or Bioanalytical chemistry and have at least 7 to 10 years of experience with immune- and cell assay development, qualification and validation in the pharmaceutical or biotech industry.

We are looking for a candidate with these qualifications:

  • Excellent lab-based scientist
  • Possession of a deep technical expertise and hands-on knowledge in a range of in vitro skills that can be applied to cancer immunology research such as
  • Common bioassay platforms (i.e. immunoassays, spectroscopy-based bioassays) and cutting-edge technologies
  • Tissue culture techniques for cell-based immunoassays, experience working with human immune cells, ex vivo immunobiology techniques such as: complex multiparameter flow cytometry (including intracellular cytokine or multicolor cell surface staining)
  • Ability to write and oversee protocol development
  • Understanding and enthusiasm for tumor immunology and cancer therapies.
  • Provide technical and operational expertise to stakeholders to ensure the delivery of high-quality assays for data generation throughout project life
  • Ability to trouble-shoot for assay optimization, characterization and validation.
  • Data processing, statistical analysis and interpretation

Additional experience of value:

  • Familiarity with risk assessments such as FMEA and designing, streamlining, and characterizing processes in the Quality by Design space
  • Experienced in the use of DOE statistical tools
  • Knowledge and experience with various HPLC/UPLC analytical techniques
  • Working in a CMC setting, including writing procedures and development reports.
  • Support technology transfer of optimized cell manufacturing processes to cGMP-compliant manufacturing facilities within the company or to CMOs
  • Knowledge within regulatory requirements of Good Manufacturing Practices (cGMP)

Join us

We offer you to become part of a fun and professional team, shaping the future of PokeAcell and creating curative treatment to cancer patients. Give us a call to discuss more if your heart is beating faster than usual and you are ready for a new endeavor.

Contact

Reach out to VP CMC and Supply Chain Development, Thomas Sandal at +45 2294 2918

Send your application via  “apply job online” at Jobindex. We prefer applications before August 7th.
Only applications from applicants already eligible to work in Denmark will be considered.